Table 1 Characteristics of PLWH and HIV-free people with SARS-CoV-2 infection in Wuhan, Hubei Province, China (N = 1,909)
PLWH (n = 687) | HIV-free (n = 1222) | p value | ||
|---|---|---|---|---|
Male | 580 (84.4%) | 484 (39.6%) | < 0.001 | |
Age, years, median (IQR) | 34 (29–42) | 35 (30–44) | 0.006 | |
BMI, kg/m2, median (IQR) | 20.05 (20.24–23.87) | 22.40 (20.57–24.77) | < 0.001 | |
COVID-19 vaccination | < 0.001 | |||
Unvaccinated | 68 (9.9%) | 42 (3.4%) | ||
One dose/two doses | 150 (21.8%) | 234 (19.1%) | ||
Three doses/four doses§ | 469 (68.3%) | 946 (77.4%) | ||
Comorbidities | 217 (31.6%) | 152 (12.4%) | < 0.001 | |
Chronic pulmonary diseases | 33 (4.8%) | 18 (1.5%) | ||
Diabetes | 17 (2.4%) | 17 (1.4%) | ||
Chronic kidney diseases | 12 (1.7%) | 4 (0.3%) | ||
Chronic liver diseases | 20 (2.9%) | 29 (2.4%) | ||
Cardiovascular and cerebrovascular diseases | 39 (5.6%) | 73 (6.0%) | ||
Autoimmune disease | 128 (18.6%) | 21 (1.7%) | ||
Cancer | 5 (0.7%) | 13 (1.1%) | ||
CD4 T count, cells/µL | ||||
0-199 | 47 (6.8%) | ·· | ·· | |
200–349 | 91 (13.2%) | ·· | ·· | |
350–499 | 179 (26.1%) | ·· | ·· | |
≥ 500 | 269 (39.2%) | ·· | ·· | |
Unknown | 101 (14.7%) | ·· | ·· | |
HIV viral load | ||||
Undetectable | 483 (70.3%) | ·· | ·· | |
Detectable | 81 (11.8%) | ·· | ·· | |
Unknown | 123 (17.9%) | ·· | ·· | |
On ART | 667 (97.1%) | ·· | ·· | |
Symptoms of SARS-CoV-2 infection | ||||
Any symptom | 604 (87.9%) | 1162 (95.1%) | < 0.001 | |
Fever | 501 (72.9%) | 1024 (83.8%) | < 0.001 | |
Nasal congestion/runny nose | 401 (58.4%) | 877 (71.8%) | < 0.001 | |
Sore/dry throat | 422 (61.4%) | 896 (73.3%) | < 0.001 | |
Headache | 408 (59.4%) | 826 (67.6%) | < 0.001 | |
Cough | 423 (61.6%) | 922 (75.5%) | < 0.001 | |
Chest pain | 68 (9.9%) | 165 (13.5%) | 0.021 | |
Chest tightness | 76 (11.1%) | 214 (17.5%) | < 0.001 | |
Fatigue | 307 (44.7%) | 740 (60.6%) | < 0.001 | |
Muscle soreness | 376 (54.7%) | 832 (68.1%) | < 0.001 | |
Decreased/lost smell | 153 (22.3%) | 439 (35.9%) | < 0.001 | |
Decreased or lost taste | 203 (29.5%) | 520 (42.6%) | < 0.001 | |
Diarrhea | 123 (17.9%) | 296 (24.2%) | 0.001 | |
Conjunctivitis | 12 (1.7%) | 38 (3.1%) | 0.074 | |
Degree of fever | < 0.001 | |||
< 37.3℃ | 186 (27.1%) | 199 (16.3%) | ·· | |
37.3–38.0℃ | 122 (17.8%) | 188 (15.4%) | ·· | |
38.1–39.0℃ | 276 (40.2%) | 542 (44.4%) | ·· | |
≥ 39.1℃ | 103 (15.0%) | 293 (24.0%) | ·· | |
Duration of fever | < 0.001 | |||
No fever | 186 (27.1%) | 199 (16.3%) | ·· | |
≤ 3 days | 403 (58.7%) | 746 (61.0%) | ·· | |
3–5 days | 84 (12.2%) | 255 (20.9%) | ·· | |
>5 days | 14 (2.0%) | 22 (1.8%) | ·· |