Table 1 Summary of clinical, biological features and therapeutic outcome of oral leishmaniasis in HIV-VL co-infected patients
Authors | Age/Gender/ Origin | History | Location and Type of oral lesions | Hepatomegaly/Splenomegaly | Other | Fever / Weigh loss | CD4/mm3 /Viral Load cp/ mm3 | Blood count | Oral biopsy/ Other | BMB/ Serology/ Other | Species | Treatment | Outcome |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Michiels JF et al.1994 [16] | 28, M/MSM France | NM | Tonsil/Palate Ulcer/polypoid | No No | Yes | Yes | 50/ NM | Anemia Pancytopenia |  +  |  + /No | ND | LAB/ ATB | D |
Pineiro TV et al. 1998 [23] | 34, M/heterosexual Spain | IVDU, HCV, Genital herpes LLei/Gluc | Tongue Nodule Ulcer | Yes No | No | Yes Yes | 140/ NM | Leucopenia |  + / KS | Neg/+ | NM | NM | D |
Nigro L et al 2003 [24] | 46, M, bisexual Italy | VL /AIDS Pulmonary Lei HAART Oral Lei | Oral mucosa Ulcer | Yes Yes | Lung | Yes, asthenia | 10/ NM | Anemia Pancytopenia hyperγGlobulinemia |  +  | +/+ | L. infantum MON1 | Gluc /60mg/kg) | Sympt |
Montineri A. et al.2007 [25] | 48 M Italy | Gingival ulcers/ Candidiasis | Gingiva Ulcer | No No | No | Yes | 334 | 54.800/MA /hyperγGlobulinemia | + | Neg/+ | NM | LAB | F/6 m |
Kumar et al 2007 [26] | 35 F India | Ulcer Tongue/ TTT for TB | Tongue Ulcer Bleeding | Yes No | No | Yes | 12/CD4 18/CD8 | Anemia | +FNA Lymph node | ND/+ | NM | NM | D |
Rodrigo L.M. et al.2007 [27] | 65, M Spain | AIDS/HCV | Palate/Uvula Ulcer | Yes Yes | No | Yes No | NM | Anemia /Thrombocytopenia | + | NM | NM | Gluc | F |
Presmanes M.M. et al 2008 [28] | 31, M Spain | IVDU, HCV,AIDS HAART, | Lower lip: Swelling Ulcer | No No | No | No Yes | 160 NM | Anemia | Neg | +/Neg | ND | LAB | F |
Diro E et al 2015 [17] | 29, F Ethiopia | Systemic symptoms Oral lesion | Palate/Mass Bleeding | Yes No | No | Yes No | 71 NM | Anemia Pancytopenia | + | + | ND | LAB ATB | D |
Present case 2017 | 43, M, heterosexual Moknine-Tunisia | HIV/HBV/TB/Anemia/Ht/S Oral swelling/ ATB | Lips/Cheeks/ Nodules | No Yes | No | No Yes | 81 Undetected | Anemia Pancytopenia |  +  | No/+/ Culture+ PCR+/ PCR RFLP+ | L infantum | LAB | F 2020: PCR+ Asympt |