Table 3 Characteristics of cases that TP0136 was detected
All cases | TP0136 not detected | TP0136 detected | P value | |||||
|---|---|---|---|---|---|---|---|---|
Number of cases | 71 | 45 | 26 | |||||
Stage of syphilis, n (%) | Primary syphilis | 7 | (9.9) | 3 | (6.6) | 4 | (15) | 0.41‡ |
Secondary syphilis | 23 | (32) | 12 | (27) | 11 | (42) | 0.19 | |
Early asymptomatic syphilis | 35 | (49) | 26 | (58) | 9 | (35) | 0.085‡ | |
Neurosyphilis* | 6 | (8.5) | 2 | (4.4) | 4 | (15) | 0.18‡ | |
Unknown | 6 | (8.5) | 4 | (8.9) | 2 | (7.8) | 0.99‡ | |
Serum TPLA titer, | Median, U/mL (IQR) | 6571 | (2582–15857) | 5209 | (2042–9858) | 11,262 | (4527–23081) | 0.0071† |
< 1000 U/mL, n | 7 | 6 | 1 | 0.056§ | ||||
1000–5000 U/mL, n | 23 | 16 | 6 | |||||
> 5000 U/mL, n | 41 | 23 | 19 | |||||
Serum RPR titer | Median, RU (IQR) | 75.7 | (34.4 -188.5) | 66.9 | (27.3–136) | 115 | (52.5–317) | 0.016† |
< 10 RU, n | 6 | 5 | 1 | 0.12§ | ||||
10–100 RU, n | 36 | 25 | 12 | |||||
> 100 RU, n | 29 | 15 | 13 | |||||
CRP | Median, mg/mL (IQR) | 0.23 | (0.09–0.65) | 0.13 | (0.06–0.31) | 0.865 | (0.575–1.29) | < 0.0001† |
< 0.1 mg/dL, n | 19 | 18 | 1 | < 0.0001§ | ||||
0.1–0.5 mg/dL, n | 26 | 21 | 5 | |||||
> 0.5 mg/dL, n | 26 | 6 | 20 | |||||