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Table 1 Baseline characteristics

From: Incidence and risk factors regarding atherosclerotic cardiovascular disease in middle-aged and elderly people with HIV treated in Chongqing, China

Variable

N = 463

low-risk group (310)

high-risk group (153)

P

Gender, n (%)

   

 < 0.001

 Male

317 (68.5)

234 (75.5)

83 (54.2)

 

 Female

146 (31.5)

76 (24.5)

70 (45.8)

 

Age, years

55.0 (50.0, 64.0)

52.0 (49.0, 57.0)

66.0 (60.0, 70.0)

 < 0.001

BMI, kg/m2

22.9 (21.1, 25.0)

22.9 (21.0, 24.8)

23.0 (21.1, 25.5)

0.633

Residence location, n (%)

   

0.003

 City

215 (46.4)

129 (41.6)

86 (56.2)

 

 Countryside

248 (53.6)

181 (58.4)

67 (43.8)

 

Married status, n (%)

   

0.174

 Married

325 (70.2)

223 (71.9)

102 (66.7)

 

 Single

138 (29.8)

87 (28.1)

51 (33.3)

 

Route of infection, n (%)

   

0.218

 Homosexual

44 (9.5)

34 (11.0)

10 (6.5)

 

 Heterosexual

318 (68.7)

206 (66.4)

112 (73.2)

 

 Unknown

101 (21.8)

70 (22.6)

31 (20.3)

 

Work status, n (%)

   

 < 0.001

 Unemployed

235 (50.8)

131 (42.3)

104 (68.0)

 

 Employed

228 (49.2)

179 (57.7)

49 (32.0)

 

Education level, n (%)

   

0.053

 Elementary school

177 (38.2)

109 (35.2)

68 (44.4)

 

 Middle school and above

286 (61.8)

201 (64.8)

85 (55.6)

 

Smoking, n (%)

   

0.519

 Yes

102 (22.0)

71 (22.9)

31 (20.3)

 

 No

361 (78.0)

239 (77.1)

122 (79.7)

 

Coffee consumption, n (%)

   

0.007

 Yes

42 (9.1)

36 (11.6)

6 (3.9)

 

 No

421 (90.9)

274 (88.4)

147 (96.1)

 

Heavy alcohol consumption, n (%)

   

0.282

 Yes

66 (14.3)

48 (15.5)

18 (11.8)

 

 No

397 (85.7)

262 (84.5)

135 (88.2)

 

Low activity levels, n (%)

   

0.396

 Yes

211 (45.6)

137 (44.2)

74 (48.4)

 

 No

252 (54.4)

173 (55.8)

79 (51.6)

 

Poor sleep quality

   

0.023

 Yes

149 (32.2)

89 (28.7)

60 (39.2)

 

 No

314 (67.8)

221 (71.3)

93 (60.8)

 

Family history of hypertension, n (%)

   

0.070

 Yes

79 (17.1)

46 (14.8)

33 (21.6)

 

 No

384 (92.9)

264 (85.2)

120 (78.4)

 

Family history of diabetes, n (%)

   

0.156

 Yes

42 (9.1)

24 (7.7)

18 (11.8)

 

 No

421 (90.9)

286 (92.3)

135 (88.2)

 

Accompanied hypertension, n (%)

    

 Yes

79 (17.1%)

20 (6.5)

40 (26.1)

 < 0.001

 No

384 (82.9)

290 (93.5)

113 (73.9)

 

Accompanied diabetes, n (%)

    

 Yes

42 (9.1%)

11 (3.5)

33 (21.6)

 < 0.001

 No

421 (90.9)

299 (96.5)

120 (78.4)

 

Duration on ART, month

38.0 (15.0, 70.3)

38.0 (15.0, 70.25)

42 (20.0, 60.50)

0.743

ART-based regimen, n (%)

   

0.163

 2NRTI + NNRTIs

238 (51.4)

166(53.5)

72 (47.1)

 

 2NRTI + PIs

41 (8.9)

30 (9.7)

11 (7.2)

 

 2NRTI + INSTIs

184 (39.7)

114 (36.8)

70 (45.7)

 

 CD4 count, (cells/mL)

322.0(202, 472)

331 (200, 481)

308.0 (204, 451)

0.566

Viral load, n (%)

   

0.368

  < 50 (copies/mL)

355 (76.7)

242 (78.1)

113 (73.9)

 

 50–200 (copies/mL)

47 (10.1)

32(10.3)

15 (9.8)

 

  > 200 (copies/mL)

61 (13.2)

36 (11.6)

25 (16.3)

 

 LDL-c (mmol/L)

2.8 (2.4, 3.2)

2.68 (2.3, 3.1)

2.94 (2.6, 3.4)

 < 0.001

 HDL-c (mmol/L)

1.3 (1.1, 1.5)

1.3 (1.0, 1.5)

1.3 (1.1, 1.6)

0.110

 TG (mmol/L)

2.8 (2.4, 3.2)

1.7 (1.1, 2.4)

1.8 (1.2, 2.6)

0.177

 TC (mmol/L)

4.9 (4.4, 5.5)

4.85 (4.3, 5.5)

5.13 (4.6, 5.9)

 < 0.001

  1. Note: Data are presented as x ± s for normally distributed data or as M (P25, P75) for skewed distributions, or N(%). Abbreviations: BMI, body mass index; ART, antiretroviral therapy; NNRTIs, non-nucleoside reverse transcriptase inhibitors; PIs, protease inhibitors; INSTIs, integrase strand transfer inhibitor; LDL-c, low-density lipoprotein cholesterol; HDL-c, high-density lipoprotein cholesterol; TG, triglyceride; TC, total cholesterol